INTERLEUKIN-27 IS A POTENT INHIBITOR OF CIS HIV-1 REPLICATION IN MONOCYTE-DERIVED DENDRITIC CELLS VIA A TYPE I INTERFERON-INDEPENDENT PATHWAY.

Interleukin-27 is a potent inhibitor of cis HIV-1 replication in monocyte-derived dendritic cells via a type I interferon-independent pathway.

IL-27, a member of the IL-12 family of cytokines, plays an important and diverse role in the function of the immune system.Whilst generally recognized as an anti-inflammatory cytokine, in addition IL-27 has been found to have broad anti-viral effects.Recently, IL-27 has been shown to be a potent inhibitor of HIV-1 infection in CD4+ T cells and macr

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Economic Situation in the Manufacturing Sector as an Example of Modern Research in Industrial Geography in Poland

The article presents change in the object of study of the industrial geography in Poland that took place in the late twentieth century with a context in the internal and external conditions of the functioning of the industrial Impact of the digital economy on the development of economic systems activities.A kind of barometer of the impact of intern

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